STUDY OF LIPID PROFILE IN STREPTOZOTOCIN (STZ) – INDUCED DIABETIC RATS UNDER NICOTINAMIDE COVERAGE TREATED WITH OCIMUM GRATISSIMUM (O.G.) AND VERNONIA AMYGDALINA (V.A.)

ABSTRACT
The effect of leaf extract of ocimum gratissimium (scent leaf) and vernonia Amygdalina (bitter leaf) under nicotinanmide coverage was studied using albino wistar rat. Acute toxicity of the plant was carried out using (Lorkes method). LD50 was calculated to be 208 mglkg. The main work involved 49 albino wistar rats weighing 150g to 200g. The rats were put in 7 groups of 7 rats each. Rats in group I served as the control and were administered distilled water and feed. Rats in Groups II-VII were administered OG, V.A, DM+NICO, DM+NICO+OG, DM+NICO+VA, DM+NICO+OG+VA respectively for 28 days according to their body weight. Oral administration was used for all the groups. The result obtained showed the mean± SEM P values (P

TABLE OF CONTENTS

Abstract

CHAPTER ONE

1.0    Introduction

1.1   Background of Study

1.2   Statement of Problems

1.3   Research Objectives

1.4   Research Question

1.5   Research Hypothesis   

1.6   Scope of Study

1.7   Significance of study

1.8   Limitation of study

1.9   Definition of terms

CHAPTER TWO

2.0   Literature Review

CHAPTER THREE

3.0   Research methodology

3.1   Research Design

3.2   Population of study

3.3   Sampling Design and Procedure

3.4   Data Collection Instrument

3.5   Administration of Data Collection Instrument

3.6   Methods of data analysis

CHAPTER FOUR

4.0   Data Presentation and Analysis

4.1   Data Presentation  

4.2   Test of Hypothesis 

CHAPTER FIVE

5.0   Summary, Conclusion and Recommendation

5.1   Summary

5.2   Conclusion

5.3    Recommendation

References

Questionnaire

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