TABLE OF CONTENTS
Abstract
CHAPTER ONE
1.0 Introduction
1.1 Background of Study
1.2 Statement of Problems
1.3 Research Objectives
1.4 Research Question
1.5 Research Hypothesis
1.6 Scope of Study
1.7 Significance of study
1.8 Limitation of study
1.9 Definition of terms
CHAPTER TWO
2.0 Literature Review
CHAPTER THREE
3.0 Research methodology
3.1 Research Design
3.2 Population of study
3.3 Sampling Design and Procedure
3.4 Data Collection Instrument
3.5 Administration of Data Collection Instrument
3.6 Methods of data analysis
CHAPTER FOUR
4.0 Data Presentation and Analysis
4.1 Data Presentation
4.2 Test of Hypothesis
CHAPTER FIVE
5.0 Summary, Conclusion and Recommendation
5.1 Summary
5.2 Conclusion
5.3 Recommendation
References
Questionnaire
ABSTRACT
Tolerance to African animal trypanosomosis (AAT) among several animal species involves a
wide milieu of factors which modulate the animal’s response to the disease and is considered a
breed attribute. To investigate the effect of breed on tolerance/resilience to trypanosome
infection on pubertal boars, nine (9) Nigerian Native and nine (9) Large-White x Landrace
crossbreed boars were experimentally inoculated with laboratory samples of Trypanosoma
brucei brucei.
Their comparative responses with regard to clinical symptoms, growth parameters,
histopathological and histometrical features of the testis, Sertoli and germ cell numbers and
spermatogenic output including cell ratios and daily sperm production were studied over two
study periods- 63 days post infection (63d p.i.) and 98 days post infection (98d p.i.). Results
obtained indicated that infected boars of both breeds were clearly parasitaemic in the first study
period, with a significant (Ptrend in the results obtained showed significant (Pwith the Nigerian Native boars exhibiting strong marginal gains by the second study period. This
was not the case with the exotic Large-White x Landrace boars and suggested that the native
boars possessed a superior ability to mitigate the more severe effects of the pathology and a
tendency to return to normal. With respect to the clinical features investigated, the Nigerian
Native boars presented significantly (Pvalues, rectal temperatures, as well as packed cell volume. Histopathological findings revealed
that lesions, including tubular distortion, denudation of basement membrane, seminiferous
epithelial damage led to the distortion of the architecture of the seminiferous epithelium as well
as degradation of the inter-tubular compartment and values were significantly (Pamong the native boars.
The parameters on growth showed the nutrient-parasite interaction was
influenced by breed attributes. Biometrical and linear body measurements were affected