CHAPTER ONE
1.0 Introduction
1.1 Amino-butyric acid
1.1.1 Biochemistry and Pharmacokinetics
1.1.2 Mechanism of action
1.1.3 Deficiency States
CHAPTER TWO
2.0 The major inhibitory neurotransmitter in nervous system
2.1 Physiology and Pharmacology of GABAA ,GABAB, GABAC Receptors
2.1.1 Structure and function of GABAA Receptors
CHAPTER THREE
3.0 Metabolism of plants
3.1 Glutamate Decarboxylase
3.2 transaminase
3.3 Succinic semialdehyde dehydrogenase
3.4 γ- Hydroxybutyric acid
3.5 shunt and the metabolism of nitrogen
3.5.1 Impact of shunt on the nitrogen metabolism
3.5.2 Regulation of shunt by nitrogen availability
CHAPTER FOUR
4.0 Clinical application
4.1 Side effects and toxicity
CHAPTER FIVE
5.0 Conclusion
References