No, Jennifer Aniston and Jay Mohr are not friends.
The pair are just colleague actors.
In 1997, Jennifer Aniston held the lead role as Kate Mosley in the romantic comedy, “Picture Perfect.” Her leading man was actor Jay Mohr, who played her love interest, Nick. On-screen, the two actors had great chemistry, but off-camera they were not.
Mohr hinted at a fissure with his co-star in a 2010 interview with Elle, in which he was asked about his most awkward interaction with a female celebrity and the comedian and actor Mohr recounted that he was once cast in a movie where the lead “made it clear” she was unhappy working with him. “I hadn’t done many movies, and even though they screen-tested some pretty famous guys, I somehow snaked into the leading role.”
“The actress said, ‘No way! You’ve got to be kidding me!’ Loudly. Between takes. To other actors on set. I would literally go to my mom’s house and cry,” Mohr disclosed.
When the Elle interviewer asked if Mohr was referring to the 1997 film “Picture Perfect” and Jennifer Aniston, the actor refused to confirm the assumption. “I will never, ever answer that,” he said.
On his “Mohr Stories” podcast, he posited that he was “elated” to get the lead role in “Picture Perfect” with no movie credits on his résumé, but when rehearsals began in Queens, New York, he found out he wasn’t liked by his leading lady. Mohr said Aniston complained about his presence on-set and loudly declared, “Six guys they screen-test! Six! … The one f**ing guy I hate, that’s the guy they hire!” “Jennifer Aniston was so f**ing mean to me,” he revealed.